Follicular Lymphoma International Prognostic Index (FLIPI)
A separate system, the FLIPI, has been developed to categorise patients with FL into groups with good, intermediate or poor prognosis. The FLIPI is based on a retrospective analysis of data from over 4,167 patients with indolent NHL, with a follow up of at least 5 years2. The model was refined to incorporate the following five predictive variables in the FLIPI index:
- ≥ 5 nodal sites
- Abnormal LDH
- Age ≤ 60 versus > 60 years
- Ann Arbor stage 3/4
- Haemoglobin <12 mg/dL
While the FLIPI was originally devised based on an analysis of chemotherapy treated patients, its application has now also been demonstrated for indolent patients receiving immunochemotherapy1.
References
- Colocci N, et al. Proc Am Soc Clin Oncol 2005:24;566s (Abstract 6526)
- Solal-Celigny P, et al. Blood. 2004 Sep 1;104(5):1258-65.
